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PhenoCode Discovery Human Neurobiology Panel
Resolve cellular and molecular brain interactions using an ultrahigh-plex neuroscience panel designed for the PhenoCycler®-Fusion.
Whether investigating neurodegenerative disease, neuroinflammation, or neuroplasticity, the PhenoCode Discovery Human Neurobiology Panel empowers you to understand key molecular and cellular interactions in the brain spatially—insights that traditional methods can’t deliver.
Key features
- Cellular characterization—identify and distinguish neuronal subtypes, glial cells, and vascular components with a well-defined set of 42 biomarkers.
- Disease-specific insights—detect neurodegenerative protein aggregates associated with Alzheimer’s disease and Parkinson’s disease, track inflammation-driven pathology, and assess blood-brain barrier integrity disruptions.
- High-impact data—use an optimized, ready-to-use panel to spatially phenotype human brain formalin-fixed paraffin-embedded (FFPE) tissues.
Fast
Designed for the fastest spatial biology solution
Optimized
Ultrahigh-plex, ready-to-use panel for easy implementation
Customizable
Add additional biomarkers using custom barcodes
Biomarkers included in the PhenoCode Discovery Human Neurobiology Panel
Neuronal cells | |
|---|---|
Mature neurons | MAP2 NeuN Neurofilament-L Synaptophysin |
GABAergic neurons | GABA |
Cholinergic neurons | CHAT |
Serotonergic neurons | Serotonin |
Neuroplasticity and cellular remodeling | |
|---|---|
Proliferation and neurogenesis | Ki67 PCNA |
Astrocyte and structural plasticity | S100B Vimentin |
Oligodendrocytes | MBP Olig2 |
Neurodegenerative disease markers | |
|---|---|
Alzheimer’s disease | Amyloid-beta ApoE p-Tau 181 p-Tau 205 p-Tau 231 p-Tau 396 |
Parkinson’s disease and synucleinopathies | Alpha-synuclein |
General neurodegeneration | H2A.X |
Blood-brain barrier integrity and vascular components | |
|---|---|
Endothelial cells and vascular structure | CD31 CD34 Claudin-5 Collagen IV |
Pericytes and smooth muscle cells | SMA |
Astrocyte-endothelial interactions | AQP4 |
Neuroinflammation and immune response | |
|---|---|
Microglia | TMEM119 |
Activated microglia and macrophages | CD68 Galectin-3 Iba1 |
T cell infiltration | CD3e CD4 CD8 |
General immune activation | CD14 CD163 CD44 CD45 HLA-A HLA-DR iNOS |
Astrocyte-associated inflammation | GFAP |
Product Details
Literature
Product Details
Product name and description
Size
Catalog number
PhenoCode Discovery Human Neurobiology Panel
Panel of 42 neuroscience biomarkers comprising antibodies and reporters.
Up to 25 slides
STPHNP001
PhenoCode Discovery Human Neurobiology Starter Pack
The PhenoCode Discovery Human Neuro Panel plus PhenoCycler-Fusion consumables for a complete solution to spatially phenotype 42 neuroscience biomarkers.
Up to 20 slides
STPHNP001_R
Literature
PhenoCode Discovery Human Neurobiology Panel
Learn about the human neuroscience spatial phenotyping panel.
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