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Spatial Omics Frontiers | Defining tumour heterogeneity, one-cell-at-a-time
Webinar | Wednesday, January 22, 2025
In this webinar, Associate Professor Arutha Kulasinghe will delve into the groundbreaking research on decoding the cellular profiles of the tumor microenvironment (TME) in cancer patients, with a focus on those who respond versus those who do not respond to immune checkpoint inhibitors. Through an in-depth analysis of lung, head and neck, and skin cancers, our speaker will explore the intricate biological mechanisms that influence patient outcomes to therapy.
The session will highlight key findings from the use of cutting-edge, integrative spatial-omics approaches. These methodologies provide a comprehensive understanding of the molecular landscape of the TME, revealing critical differences in cell populations between responders and non-responders.
Video
Speaker
Arutha Kulasinghe, PhD
Scientific Director of the Queensland Spatial Biology Center in Brisbane, Group Leader at The University of Queensland
Biography
Arutha Kulasinghe is a Peter Doherty NHMRC Research Fellow and leads the 'Clinical-oMx Lab' at the University of Queensland. Kulasinghe has pioneered spatial transcriptomics using digital spatial profiling approaches in the Asia-Pacific region, contributing to world-first studies for lung cancer, head and neck cancer, and COVID-19. His research aims to understand the underlying pathobiology by using an integrative multi-omics approach. Kulasinghe has published his research in 60 manuscripts and is supported by the NHMRC, the Australian Academy of Sciences, Cancer Australia, Cure Cancer, MRFF, and numerous philanthropic and hospital foundations.